PEGASUS® BT 4D
GC×GC Time-of-Flight Mass Spectrometer
The Pegasus BT 4D offers enhanced sensitivity by coupling our benchtop Pegasus BT with a high performance GC×GC modulation system. This combination gives the Pegasus BT 4D the ability to interrogate challenging samples where the best sensitivity is needed. Unique and powerful software and hardware features simplify quantitation, while also dramatically making GC×GC easy-to-use and understand.
Our traditional thermal modulation system provides the highest sensitivity available on the market for those analyzing the most complex samples.
Our new FLUX™ flow modulation system is an excellent option for those looking for added capability over one dimensional GC.
What is GC×GC?
Comprehensive two-dimensional gas chromatography (GC×GC) is a technique that has been around for over 25 years. Some may argue that the technique has been over-hyped, and that it is a complicated research tool that doesn’t fit into routine analytical laboratories. However, several routine validated GC×GC methods have demonstrated that the technique is accurate, precise, and robust. Research has shown the benefits of GC×GC in a wide variety of applications (e.g. environmental, metabolomics, petroleum, food safety, fragrance). The benefits include increased peak capacity (i.e. resolution), structured two-dimensional chromatograms (i.e. contour plots), and sensitivity enhancement. The merits of GC×GC as a separation science are clear, but how will it benefit a routine laboratory? Multiple analyte classes can be combined into a single analysis to save instrument and sample preparation time. Manual review time for non-target screening methods can be reduced with the increased peak resolution of a GC×GC analysis by creating a better library match leading to faster, more confident peak identification. Sample characterization is improved with a GC×GC analysis which increases confidence in decisions based on analytical results. The extra resolution afforded by the GC×GC analysis allows the use of more economical detectors, like the flame ionization detector (FID) or electron capture detector (ECD).
Download this free whitepaper: Benefits of Comprehensive Two-Dimensional Gas Chromatography (GC×GC) for a Routine Laboratory, authored by Michelle Misselwitz, for more information on how GC×GC can benefit your laboratory.
PEGASUS® BT 4D Details
- Pegasus BT 4D with FLUX Flow Modulator
- Pegasus BT 4D with Liquid Nitrogen Thermal Modulator
- Pegasus BT 4D with Cryogen-Free Thermal Modulator
- L-PAL3 Automated Sample Injector
Determining Terpene Profiles of Cannabis Strains
Pegasus BT 4D
That‘s what our users say:
Helmholtz Zentrum München (HMGU) Department “Comprehensive Molecular Analytics“, GERMANY
„This combination of ultrahigh chromatographic separation with high mass resolution might be still unique for a commercial
available end user system.“
Food Chemistry Institute Cologne, Italy
“Pegasus BT is the perfect choice for identifying well-known metabolites at low concentration level in our sample, and also discovering new compounds. The most surprising advantage of the BT system is the ion source robustness! We usually work with dirty and complex samples, but we have never observed drop of sensitivity during our analyses.This reduces the time and cost of our analyses!”
Università degli Studi del Piemonte Orientale, Italy
„With the Pegasus BT 4D performing untargeted analysis today is very easy, thanks to the high sensitivity of the instrument, we are able to mine and analyze any type of sample! A combination of very good sensitivity, quality to price ratio and high flexibility make the Pegasus BT 4D system perfect for analysis of every sample”
Czech Academy of Science, Tschechische Republik
“Compared to GC equipped with a single column, the Pegasus 4D enabled me to separate unbelievable number of analytes! Tens of thousands of separated peaks in one run was not an exception. But where the separation was not perfect, ChromaTOF software and its deconvolution algorithm did the job. Such excellent ‘separating power’ helped me discover new types of plant PCB metabolites.“
TURKU Metabolomics Facility, Finland
“We use the LECO Pegasus BT instrument for the quantiﬁcation of small polar metabolites. We developed a hybrid method where we quantitate 51 metabolites with standard curves and screen for any other small polar metabolites in a wide range of biological samples. This assay has a great dynamic range thanks to the sensitivity of the BT. The StayClean® ion source allows us to run hundreds of samples in a batch and be conﬁ dent that the ion source will remain clean even with dirty samples such as plasma.“
SGS Institut Fresenius GmbH Berlin, Germany
“We at SGS MOSH/MOAH group are using the GC × GC-TOFMS from LECO to separate the highly complex fractions of MOSH/MOAH contaminates in food. When you want to identify special patterns of contamination species amongst other analytics (e. g carotenoids) you need a high separation power in combination with a fast screening MS. This is provided by the LECO TOF. Actually we have a new project together with LECO and another company to quantify MOSH/MOAH fractions. The complexity of the instrumentation is high, but with the support of the application team from LECO we reach our goals.”
ALS Enviromental, UK
“I believe this technology and methodology will profoundly change water analysis realising major beneﬁ ts for both laboratories and their customers.“
LECO INSTRUMENTS UK LTD.
Unit 7, Rhino Court, Station View
Bramhall More Lane, Hazel Grove
Stockport SK7 5ER
Phone: +44 161 487 5900